| Clobetasol Propionate Impurity E is an impurity of Clobetasol, which is a topical corticosteroid. Glucocorticoid, anti-inflammatory. Synonyms: (8R,9S,10R,13S,14S,16S,17R)-17-(2-Chloroacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate Molecular Formula: C25H33ClO4 Molecular Weight: 432.98 Solubility: Chloroform (Slightly), DMSO (Slightly) Purity: 95% Appearance: White to off-white solid Method for Determining Identity: Proton NMR Spectroscopic and Mass Spectrometric Analysis TLC Conditions: SiO2, Ethyl Acetate : Hexanes = 1 : 1, Visualized with UV, AMCS, and KMnO4, Single Spot, Rf = 0.60 Elemental Analysis: Calculated: %C: 69.35, %H: 7.68 Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |
