Dolutegravir-d6 is an isotopic analog of Dolutegravir which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. Synonyms: (4R,12aS)-N-[(2,4-Difluorophenyl)methyl-d2]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-(methyl-d3)-6,8-dioxo-2H-pyrido[1,2:4,5]pyrazino[2,1-b][1,3]oxazine-4-d-9-carboxamide CAS No: 1407166-95-3 Unlabelled: 1051375-16-6 Molecular Formula: C20H13D6F2N3O5 Molecular Weight: 425.42 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
425.42
CAS Nummer:
[1407166-95-3]
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