DY-268 is a trisubstituted-pyrazol carboamide based compound that acts as a potent FXR antagonist (IC50 = 7.5 nM). It does not display any FXR agonistic activity and cytotoxicity. Synonyms: 1-(3-Methoxybenzyl)-N-(4-methyl-3-(morpholinosulfonyl)phenyl)-3-(p-tolyl)-1H-pyrazole-4-carboxamide, 1-[(3-Methoxyphenyl)methyl]-N-[4-methyl-3-(4-morpholinylsulfonyl)phenyl]-3-(4-methylphenyl)-1H-pyrazole-4-carboxamide CAS No: 1609564-75-1 Molecular Formula: C30H32N4O5S Molecular Weight: 560.66 Solubility: DMSO, 50-100mg/ml Biological Activity: Potent FXR antagonist (IC50 = 7.5 nM). Exhibits no detectable cytotoxicity in cell-based assays. Appearance: White to off-white powder Purity 98% (HPLC) Storage and Stability: Store at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
560.66
Reinheit:
98% (HPLC)
Formulierung:
White to off-white powder
CAS Nummer:
[1609564-75-1]
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