Protein Kinase C (PKC) inhibitor, an ether lipid derivative of lysophosphatidylcholine has antineoplastic activity in vitro and in vivo. IC50 = 560nM. Competitive at the regulatory site of PKC. Ilmofosine is active against a variety of explanted human non-small cell lung, breast, colorectal, ovarian, renal cell cancer, and melanoma tumors in vitro at concentrations of 1-30ug/ml. Synonyms: 1-Hexadecylmercapto-2-methoxymethyl-3-propyl Phosphoric Acid Monocholine Ester, BM 41440, Thio ALP CAS No: 83519-04-4 Molecular Formula: C26H56NO5PS Molecular Weight: 525.77 Solubility: H2O (10mg/ml) Method for Determining Identity: Proton NMR Purity: 97% (NMR) Appearance: Semisolid (waxy) Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
525.77
Reinheit:
97% (NMR)
Formulierung:
Semisolid (waxy)
CAS Nummer:
[83519-04-4]
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