Sulfo-Cy 5 NHS Ester can be used in biological and analytical studies of in situ ion-transmission mass spectrometry for paper-based analytical devices. A variety of cyanine dyes has been used to label biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis. They are widely used for labeling peptides, proteins and oligos etc. Cy5 dyes are one type of the most common red fluorophores. These versatile fluorophores can tolerate a pH range of 3-10 for use in a variety of applications at biologically relevant pHs. The dyes are also DMSO tolerant and photostable to enable transfer from storage to assay without loss of performance. The aqueous solubility eliminates the need for organic solvents in the assay buffers. Sulfo-Cyanine 5 is an alternative dye primarily used for labeling peptides and oligos in replacing Cy5 that was originally developed by GE Healthcare (Cy5 is the trademark of GE Healthcare). NHS ester dyes are recommended for labeling amine groups and maleimide dyes are recommended for labeling thiol groups. This Cy5 NHS ester readily reacts with amino groups. Synonyms: diSulfo-Cy5 NHS Ester, Lumiprobe Sulfo-Cy5.0 NHS Ester, Lumiprobe Sulfo-Cyanine 5 NHS Ester, 2- [5- (1, 3- dihydro- 1, 3, 3- trimethyl- 5- sulfo- 2H- indol- 2- ylidene) - 1, 3- pentadien- 1- yl] - 1- [6-[(2,5-dioxo-1-pyrrolidinyl) oxy]-6- oxohexyl] - 3, 3- dimethyl- 5- sulfo-3H- indolium Inner Salt Sodium Salt CAS Number: 1448789-45-4 Molecular Formula: C36H40N3NaO10S2 Molecular Weight: 761.84 Appearance: Supplied as a solid Solubility: DMSO, DMF, Water Storage and Stability: Store at -20C under inert atmosphere. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Warm the tube at 37C and shake it in the ultrasonic bath. Stock solution can be stored below -20C for several months.
Molekulargewicht:
761.84
CAS Nummer:
[1448789-45-4]
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