Palbociclib (also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. Palbociclib is a highly specific inhibitor of Cdk4 and Cdk6 with IC50s of 11nM and16nM. Synonyms: PD-0332991, 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(1-piperazinyl)-2-pyridinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, Palbocyclib CAS No: 571190-30-2 Molecular Formula: C24H29N7O2 Molecular Weight: 447.54 Appearance: White to off-white solid Purity: 99% (HPLC) NMR, MS: Conforms to reference Melting Point: >244C (dec.) Solubility: Chloroform (Slightly), DMSO (Slightly, Heated) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
447.54
Reinheit:
99% (HPLC)
Formulierung:
White to off-white solid
CAS Nummer:
[571190-30-2]
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