RMM 46 is a reversible covalent inhibitor that exhibits high ligand efficiency and selectivity for MSK/RSK-family kinases. A reversible covalent inhibitor targeting MSK/RSK family kinases (MSK1, MSK2, RSK2, RSK3) and also shown to inhibit eIF2A, leading to reduced protein synthesis. Synonyms: 2-Cyano-N-(2-hydroxy-1,1-dimethylethyl)-3-[3-(3, 5-trimethoxyphenyl)-1H-indazol-5-yl]-2-propenamide CAS No: 1307896-46-3 Molecular Formula: C24H26N4O5 Molecular Weight: 450.49 Purity: 97% (HPLC) Appearance: Yellow solid Solubility: DMSO: 100mM Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
450.49
CAS Nummer:
[1307896-46-3]
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