Selonsertib is an apoptosis signal-regulating kinase 1 (ASK1) inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. Selonsertib interacts with the catalytic kinase domain of ASK1 and prevents its phosphorylation and activation. As a result, the expression of genes involved in fibrosis, cellular proliferation, and apoptosis are down regulated. Molecular Formula: C24H24FN7O Solubility: DMSO (Slightly), Methanol (Slightly) Molecular Weight: 445.49 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
445.49
Formulierung:
Supplied as a Off-White to Pale Yellow Solid
CAS Nummer:
[1448428-04-3]
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