Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2-deoxy-2-alpha-fluoro-beta-C-methyluridine-5-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Molecular Formula: C22H29FN3O9P Solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly) Molecular Weight: 529.45000000000005 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
529.45
Formulierung:
Supplied as a white to off-white solid.
CAS Nummer:
[1190308-01-0]
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