Substance P is a neurokinin undecapeptide neurotransmitter and neuromodulator. Neuropeptide found in high concentrations in the gut. When released from afferent nerves, causes a neurogenic inflammatory response, including mast cell degranulation. Induces Ca2+ mobilization. Reported to activate Goalpha, Gq/11alpha, and Gsalpha subunits in CHO cells via activation of substance P receptors. Also reported to induce superoxide production in neutrophils. Sequence: H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 CAS No: 33507-63-0 Molecular Formula: C63H98N18O13S Molecular Weight: 1347.63 Solubility: DMSO, Water, 5% acetic acid, 1mg/ml Appearance: White powder trifluoroacetate salt Purity: 96% (HPLC) Storage and Stability: Store at -20C. Hygroscopic under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
1347.63
Reinheit:
96% (HPLC)
Formulierung:
White powder trifluoroacetate salt
CAS Nummer:
[33507-63-0]
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