Epacadostat is a potent and novel indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10nM. It has high selectivity over IDO2 and tryptophan 2,3-dioxygenase (TDO). Synonyms: C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide, INCB 024360 CAS Number: 1204669-58-8 Molecular Weight: 438.23 Molecular Formula: C11H13BrFN7O4S Purity (HPLC): 98% Appearance: White to off-white solid Melting Point: 159-161C (lit) Solubility: DMSO-d6 Method for Determining Identity: Proton NMR and Mass Spectroscopic Analysis Storage and Stability: Store at -20C. Caution: Hygroscopic, Store under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap
Molekulargewicht:
438.23
CAS Nummer:
[1204669-58-8]
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