BCAS1 (Breast Carcinoma-Amplified Sequence 1), Rabbit

Artikelnummer: USB-476145
Artikelname: BCAS1 (Breast Carcinoma-Amplified Sequence 1), Rabbit
Artikelnummer: USB-476145
Hersteller Artikelnummer: 476145
Alternativnummer: USB-476145-100
Hersteller: US Biological
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Immunogen: Synthetic peptide corresponding to the C-terminal region of human BCAS1
This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. Two transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI: 003648
UniProt: O75363
Reinheit: Purified by affinity chromatography.
Formulierung: Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.