CD3E (T-Cell Surface Glycoprotein CD3 Epsilon Chain, CD3e Molecule, Epsilon (CD3-TCR Complex)), Rabbit

Artikelnummer: USB-477510
Artikelname: CD3E (T-Cell Surface Glycoprotein CD3 Epsilon Chain, CD3e Molecule, Epsilon (CD3-TCR Complex)), Rabbit
Artikelnummer: USB-477510
Hersteller Artikelnummer: 477510
Alternativnummer: USB-477510-100
Hersteller: US Biological
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Immunogen: Synthetic peptide corresponding to the middle region of human CD3E
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI: 000724
UniProt: P07766
Reinheit: Purified by affinity chromatography.
Formulierung: Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.