CXCR1 (C-X-C Chemokine Receptor Type 1, Chemokine (C-X-C Motif) Receptor 1), Rabbit

Artikelnummer: USB-478847
Artikelname: CXCR1 (C-X-C Chemokine Receptor Type 1, Chemokine (C-X-C Motif) Receptor 1), Rabbit
Artikelnummer: USB-478847
Hersteller Artikelnummer: 478847
Alternativnummer: USB-478847-100
Hersteller: US Biological
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Immunogen: Synthetic peptide corresponding to the middle region of human CXCR1
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI: 000625
UniProt: C9JW47
Reinheit: Purified by affinity chromatography.
Formulierung: Supplied as a liquid in PBS, 23% sucrose, 0.09% sodium azide.