CYP8B1 (7-Alpha-Hydroxycholest-4-en-3-one 12-Alpha-Hydroxylase, Cytochrome P450, Family 8, Subfamily B, Polypeptide 1), Rabbit
Artikelnummer:
USB-478978
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| Artikelname: | CYP8B1 (7-Alpha-Hydroxycholest-4-en-3-one 12-Alpha-Hydroxylase, Cytochrome P450, Family 8, Subfamily B, Polypeptide 1), Rabbit |
| Artikelnummer: | USB-478978 |
| Hersteller Artikelnummer: | 478978 |
| Alternativnummer: | USB-478978-100 |
| Hersteller: | US Biological |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Immunogen: | Synthetic peptide corresponding to the middle region of human CYP8B1 |
| This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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