FGR (Tyrosine-Protein Kinase Fgr, FGR Proto-Oncogene, Src Family Tyrosine Kinase), Rabbit
Artikelnummer:
USB-481078
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| Artikelname: | FGR (Tyrosine-Protein Kinase Fgr, FGR Proto-Oncogene, Src Family Tyrosine Kinase), Rabbit |
| Artikelnummer: | USB-481078 |
| Hersteller Artikelnummer: | 481078 |
| Alternativnummer: | USB-481078-100 |
| Hersteller: | US Biological |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Immunogen: | Synthetic peptide corresponding to the middle region of human FGR |
| This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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