ISCU (iron-Sulfur Cluster Assembly Enzyme ISCU, Mitochondrial, Iron-Sulfur Cluster Assembly Enzyme), Rabbit
Artikelnummer:
USB-483711
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| Artikelname: | ISCU (iron-Sulfur Cluster Assembly Enzyme ISCU, Mitochondrial, Iron-Sulfur Cluster Assembly Enzyme), Rabbit |
| Artikelnummer: | USB-483711 |
| Hersteller Artikelnummer: | 483711 |
| Alternativnummer: | USB-483711-100 |
| Hersteller: | US Biological |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Immunogen: | Synthetic peptide corresponding to the middle region of human ISCU |
| Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. A pseudogene of this gene is present on chromosome 1. Alternative splicing results in multiple transcript variants encoding different isoforms. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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