Multidrug Resistance-Associated Protein 1, Recombinant, Human, aa1248-1531, His-Tag (ABCC1)

Produktübersicht

• Artikelname: Multidrug Resistance-Associated Protein 1, Recombinant, Human, aa1248-1531, His-Tag (ABCC1)
• Artikelnummer: USB-518011
• Hersteller Artikelnummer: 518011
• Alternativnummer: USB-518011-20,USB-518011-100,USB-518011-1
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency. Source: Recombinant protein corresponding to aa1248-1531 of human Multidrug Resistance-Associated Protein 1, fused to 6xHis-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~35.9kD AA Sequence: VRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMA kDaGLV Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 35.9
• UniProt: P33527
• Reinheit: 90% (SDS-PAGE)
• Formulierung: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.