Agrin, Recombinant, Rat, aa997-1753, His-Tag

Produktübersicht

• Artikelname: Agrin, Recombinant, Rat, aa997-1753, His-Tag
• Artikelnummer: USB-532252
• Hersteller Artikelnummer: 532252
• Alternativnummer: USB-532252-50,USB-532252-100
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

Agrin, also known as AGRN, is a large proteoglycan whose best-characterized role is in the development of the neuromuscular junction during embryogenesis. Agrin is named based on its involvement in the aggregation of acetylcholine receptors during synaptogenesis The agrin gene is expressed in rat embryonic nervous system and muscle. This protein is concentrated at synapses, where it may play a role in development and regeneration. When secreted, agrin binds to several receptors on the surface of skeletal muscle. Recombinant protein corresponding to aa997-1753 from rat Agrin, fused to His-Tag, at C-terminal, expressed in Baculovirus. Molecular Weight: ~82.5kDa (766aa) Amino Acid Sequence: ADPSCYNSPL GCCSDGKTPS LDSEGSNCPA TKAFQGVLEL EGVEGQELFY TPEMADPKSE LFGETARSIE STLDDLFRNS DVKKDFWSVR LRELGPGKLV RAIVDVHFDP TTAFQASDVG QALLRQIQVS RPWALAVRRP LQEHVRFLDF DWFPTFFTGA ATGTTAAMAT ARATTVSRLP ASSVTPRVYP SHTSRPVGRT TAPPTTRRPP TTATNMDRPR TPGHQQPSKS CDSQPCLHGG TCQDQDSGKG FTCSCTAGRG GSVCEKVQPP SMPAFKGHSF LAFPTLRAYH TLRLALEFRA LETEGLLLYN GNARGKDFLA LALLDGRVQF RFDTGSGPAV LTSLVPVEPG RWHRLELSRH WRQGTLSVDG ETPVVGESPS GTDGLNLDTN LYVGGIPEEQ VAMVLDRTSV GVGLKGCIRM LDINNQQLEL SDWQRAAVQS SGVGECGDHP CLPNPCHGGA LCQALEAGMF LCQCPPGRFG PTCADEKSPC QPNPCHGAAP CRVLSSGGAK CECPLGRSGT FCQTVLETAG SRPFLADFNG FSYLELKGLH TFERDLGEKM ALEMVFLARG PSGLLLYNGQ KTDGKGDFVS LALHNRHLEF CYDLGKGAAV IRSKEPIALG TWVRVFLERN GRKGALQVGD GPRVLGESPK SRKVPHTMLN LKEPLYIGGA PDFSKLARGA AVSSGFSGVI QLVSLRGHQL LTQEHVLRAV DVSPFADHPC TQALGNPCLN GGSCVPREAT YECLCPGGFS GLHCEKGLVE HHHHHH Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 82.5
• NCBI: 786930
• UniProt: P25304
• Reinheit: 90% (SDS-PAGE) Endotoxin: 1EU/ug (LAL).
• Formulierung: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.