B7-2/CD86, Recombinant, Human, aa31-247, His-Tag
Artikelnummer:
USB-532262
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| Artikelname: | B7-2/CD86, Recombinant, Human, aa31-247, His-Tag |
| Artikelnummer: | USB-532262 |
| Hersteller Artikelnummer: | 532262 |
| Alternativnummer: | USB-532262-50,USB-532262-100,USB-532262-250,USB-532262-500 |
| Hersteller: | US Biological |
| Kategorie: | Molekularbiologie |
| B7-2/CD86, also known as T-lymphocyte activation antigen CD86 isoform 1, is a variably glycosylated protein in the B7 family. These family members play important roles in immune activation and the maintenance of immune tolerance. It is expressed on antigen-presenting cells that provides co-stimulatory signals necessary for T cell activation and survival and exists predominantly as a monomer on cell surfaces. Also, it interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells that it induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. Recombinant protein corresponding to aa31-247 from human B7-2/CD86, fused to His-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~25.6kD (223aa) Amino Acid Sequence: YFNETADLPC QFANSQNQSL SELVVFWQDQ ENLVLNEVYL GKEKFDSVHS KYMGRTSFDS DSWTLRLHNL QIKDKGLYQC IIHHKKPTGM IRIHQMNSEL SVLANFSQPE IVPISNITEN VYINLTCSSI HGYPEPKKMS VLLRTKNSTI EYDGIMQKSQ DNVTELYDVS ISLSVSFPDV TSNMTIFCIL ETDKTRLLSS PFSIELEDPQ PPPDHIPHHH HHH Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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