B7-H3, Recombinant, Mouse, aa29-248, His-Tag

Produktübersicht

• Artikelname: B7-H3, Recombinant, Mouse, aa29-248, His-Tag
• Artikelnummer: USB-532263
• Hersteller Artikelnummer: 532263
• Alternativnummer: USB-532263-50,USB-532263-100
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

B7H3, also known as CD276 antigen, is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. This protein plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. It induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. Recombinant protein corresponding to aa29-248 from mouse B7-H3, fused to His-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~24.7kD (226aa) Amino Acid Sequence: VEVQVSEDPV VALVDTDATL RCSFSPEPGF SLAQLNLIWQ LTDTKQLVHS FTEGRDQGSA YSNRTALFPD LLVQGNASLR LQRVRVTDEG SYTCFVSIQD FDSAAVSLQV AAPYSKPSMT LEPNKDLRPG NMVTITCSSY QGYPEAEVFW KDGQGVPLTG NVTTSQMANE RGLFDVHSVL RVVLGANGTY SCLVRNPVLQ QDAHGSVTIT GQPLTFPPEA HHHHHH Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 24.7
• NCBI: 598744
• UniProt: Q8VE98
• Reinheit: 90% (SDS-PAGE). Endotoxin: 1EU/ug (LAL).
• Formulierung: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.