CD8 alpha, also known as T-cell surface glycoprotein CD8 alpha chain isoform 1, is a member of integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses. It interacts with the T-cell receptor and the MHC class I proteins presented by antigen presenting cells. Homodimers of this protein at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells in NK-cells. Recombinant protein corresponding to aa22-182 from human CD8 alpha fused to His-tag at C-terminal, expressed in Baculovirus.. Molecular Weight: ~18.7kD (170aa) Amino Acid Sequence: ADPSQFRVSP LDRTWNLGET VELKCQVLLS NPTSGCSWLF QPRGAAASPT FLLYLSQNKP KAAEGLDTQR FSGKRLGDTF VLTLSDFRRE NEGYYFCSAL SNSIMYFSHF VPVFLPAKPT TTPAPRPPTP APTIASQPLS LRPEACRPAA GGAVHTRGLD FACDHHHHHH Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.