CTRP5/C1qTNF5, Recombinant, Human, aa16-243, His-Tag
Artikelnummer:
USB-532288
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| Artikelname: | CTRP5/C1qTNF5, Recombinant, Human, aa16-243, His-Tag |
| Artikelnummer: | USB-532288 |
| Hersteller Artikelnummer: | 532288 |
| Alternativnummer: | USB-532288-50,USB-532288-100 |
| Hersteller: | US Biological |
| Kategorie: | Molekularbiologie |
| TRP5, also known as Complement C1q tumor necrosis factor-related protein 5, encodes a short-chain collagen which is strongly expressed in sub-retinal pigment epithelium (sub-RPE), ciliary epithelium and adipose tissue. CTRP5 is increased in mtDNA-depleted myocytes and that it stimulates the phosphorylation of AMP activated protein kinase. CTRP5 plays an important role in the adhesion of the retinal pigment epithelium (RPE) to the Bruch Membrane, and mutations are thought to impair the adhesion, resulting in sub-RPE deposits. Recombinant protein corresponding to aa16-243 from human CTRP5, fused to His-Tag at N-terminal expressed in E. coli. Molecular Weight: ~24.6kD (210aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMSPPLD DNKIPSLCPG HPGLPGTPGH HGSQGLPGRD GRDGRDGAPG APGEKGEGGR PGLPGPRGDP GPRGEAGPAG PTGPAGECSV PPRSAFSAKR SESRVPPPSD APLPFDRVLV NEQGHYDAVT GKFTCQVPGV YYFAVHATVY RASLQFDLVK NGESIASFFQ FFGGWPKPAS LSGGAMVRLE PEDQVWVQVG VGDYIGIYAS IKTDSTFSGF LVYSDWHSSP VFA Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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