FGF-21, also known as fibroblast growth factor 21, is a member of the fibroblast growth factor family. It has a hydrophobic N-terminal, which is a typical signal sequence, and appears to be a secreted protein. It stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression. Recombinant protein corresponding to aa29-210 from mouse FGF-21, fused to His-tag at N-terminal, expressed in E. coli.. Molecular Weight: ~22.5kD (206aa), confirmed by MALDI-TOF Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSF MSGMAYPIPD SSPLLQFGGQ VRQRYLYTDD DQDTEAHLEI REDGTVVGAA HRSPESLLEL KALKPGVIQI LGVKASRFLC QQPDGALYGS PHFDPEACSF RELLLEDGYN VYQSEAHGLP LRLPQKDSPN QDATSWGPVR FLPMPGLLHE PQDQAGFLPP EPPDVGSSDP LSMVEPLQGR SPSYAS Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.