Partial recombinant protein corresponding to aa215-314 from human ADAM17, fused to GST-Tag. MW of the GST tag alone is 26kD. Species sequence homology: mouse and rat
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes