COMMD7 (COMM Domain Containing 7) contains 1 COMM domain. It interacts (via COMM domain) with COMMD1 via its COMM domain and also associates with the NF-kappa-B complex and suppresses its transcriptional activity. COMMD7 is widely expressed with highest expression in lung. Vector Description: This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector. cDNA Size: 603bp Preparation before Usage: 1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid. Nucleotide Sequence: ATGGGCCGCCTGCACTGCACTGAGGACCCGGTGCCGGAGGCCGTGGGCGGCGACATGCAGCAGCTGAACCAGCTGGGCGCGCAGCAGTTCTCAGCCCTGACAGAGGTGCTTTTCCACTTCCTAACTGAGCCAAAAGAGGTGGAAAGATTTCTGGCTCAGCTCTCTGAATTTGCCACCACCAATCAGATCAGTCTTGGCTCCCTCAGAAGCATCGTGAAAAGCCTCCTTCTGGTTCCAAATGGTGCTTTGAAGAAGAGTCTCACAGCCAAGCAGGTCCAGGCGGATTTCATAACTCTGGGTCTTAGTGAGGAGAAAGCCACTTACTTTTCTGAAAAGTGGAAGCAGAATGCTCCCACCCTTGCTCGATGGGCCATAGGTCAGACTCTGATGATTAACCAGCTCATAGATATGGAGTGGAAATTTGGAGTGACATCTGGGAGCAGCGAATTGGAGAAAGTGGGAAGTATATTTTTACAACTAAAGTTGGTGGTTAAGAAAGGAAATCAAACCGAAAATGTGTATATAGAATTAACCTTGCCTCAGTTCTACAGCTTCCTGCACGAGATGGAGCGAGTCAGAACCAGCATGGAGTGTTTCTGCTGA Translation Sequence: MGRLHCTEDP VPEAVGGDMQ QLNQLGAQQF SALTEVLFHF LTEPKEVERF LAQLSEFATTNQISLGSLRS IVKSLLLVPN GALKKSLTAK QVQADFITLG LSEEKATYFS EKWKQNAPTLARWAIGQTLM INQLIDMEWK FGVTSGSSEL EKVGSIFLQL KLVVKKGNQT ENVYIELTLPQFYSFLHEME RVRTSMECFC Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
