MBIP inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. This protein is a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Vector Description: This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector. cDNA Size: 1035bp Preparation before Usage: 1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid. Nucleotide Sequence: ATGGCTGCTGCCACGGAGCTTAATCGCCCGAGCAGCGGTGACAGGAACCTGGAGCGAAGATGCAGACCCAACCTCTCCCGAGAGGTGCTCTACGAAATCTTTCGCTCCCTACACACCCTGGTTGGACAGCTTGACCTCAGAGATGATGTGGTGAAAATTACAATCGATTGGAACAAGCTCCAGAGCCTCTCGGCATTCCAGCCTGCATTGCTCTTTAGTGCACTTGAACAACACATTTTATATTTACAGCCTTTTTTAGCAAAACTTCAGTCTCCGATTAAAGAGGAGAATACAACTGCTGTTGAAGAGATAGGAAGAACAGAAATGGGGAACAAAAATGAAGTAAATGACAAATTTTCCATTGGCGACCTACAAGAGGAAGAAAAGCACAAAGAAAGTGATTTAAGAGATGTGAAAAAGACACAGATCCATTTTGATCCAGAAGTAGTTCAGATAAAGGCTGGAAAAGCAGAAATTGACAGACGAATATCTGCATTTATTGAAAGAAAGCAAGCTGAAATCAATGAAAACAACGTCAGGGAATTTTGCAATGTTATTGATTGTAATCAAGAAAATAGTTGTGCAAGAACTGATGCGATTTTTACCCCTTACCCCGGATTTAAAAGTCACGTAAAAGTTTCTAGAGTTGTGAATACATACGGACCACAGACTAGACCTGAAGGAATTCCAGGGTCAGGTCATAAACCTAACAGCATGCTTCGAGACTGTGGTAATCAGGCTGTAGAAGAACGACTACAAAATATTGAGGCCCACTTGCGGTTACAGACAGGTGGTCCAGTGCCAAGAGACATTTATCAGAGAATTAAAAAACTTGAGGATAAAATCCTTGAATTGGAAGGCATCTCTCCTGAATATTTTCAGTCTGTAAGCTTTTCTGGAAAAAGAAGAAAAGTTCAACCACCTCAACAGAACTATTCACTGGCTGAACTTGATGAGAAAATTAGTGCCCTCAAACAAGCCCTCCTCAGAAAATCAAGAGAAGCAGAATCCATGGCAACCCACCACCTTCCATGA Translation Sequence: MAAATELNRP SSGDRNLERR CRPNLSREVL YEIFRSLHTL VGQLDLRDDV VKITIDWNKLQSLSAFQPAL LFSALEQHIL YLQPFLAKLQ SPIKEENTTA VEEIGRTEMG NKNEVNDKFSIGDLQEEEKH KESDLRDVKK TQIHFDPEVV QIKAGKAEID RRISAFIERK QAEINENNVREFCNVIDCNQ ENSCARTDAI FTPYPGFKSH VKVSRVVNTY GPQTRPEGIP GSGHKPNSMLRDCGNQAVEE RLQNIEAHLR LQTGGPVPRD IYQRIKKLED KILELEGISP EYFQSVSFSGKRRKVQPPQQ NYSLAELDEK ISALKQALLR KSREAESMAT HHLP Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
