IL-1 is a inflammatory cytokine produced by activated macrophages. IL-1 is active in the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. IL-1 acts on Th cells and causes them to secrete IL-2, which induces T cells to undergo mitosis and clonal expansion (Straw Barbara, Diseases of Swine -9th edition). Source: Recombinant protein corresponding to aa113-270 from porcne IL-1 alpha, expressed in Pichia pastoris Molecular Weight: ~18.10kD Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile PBS, 0.1% carrier protein. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
