Solithromycin is a fluoroketolide with potent activity against bacterial pathogens that are susceptible or resistant to other macrolide antibiotics. Solithromycin binds to the large 50S subunit of the ribosome inhibiting protein biosynthesis, and is a potent inhibitor of cytokine (TNF-alpha and IL-8) release and matrix metalloproteinase (MMP) expression. Solithromycin is active against Gram-positive, fastidious Gram-negative organisms, including Neisseria gonorrheae, and Plasmodium sp. Synonyms: CEM 101, OP 1068, Solithera CAS No: 760981-83-7 Molecular Formula: C43H65FN6O10 Molecular Weight: 845 Purity: 95% (HPLC) Appearance: White solid Solubility: Methanol, DMSO. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with ethanol, methanol or DMSO.. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molekulargewicht:
845
CAS Nummer:
[760981-83-7]
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
