A-769662 (6,7-Dihydro-4-hydroxy-3-(2-hydroxy[1,1-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile), CAS [[844499-71-4]]

Produktübersicht

• Artikelname: A-769662 (6,7-Dihydro-4-hydroxy-3-(2-hydroxy[1,1-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile), CAS [[844499-71-4]]
• Artikelnummer: USB-A0001-68U
• Hersteller Artikelnummer: A0001-68U
• Alternativnummer: USB-A0001-68U-10
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

A-769662 is a potent, reversible activator of AMP-activated protein kinase (AMPK). AMPK is an alpha beta gamma heterotrimer and plays an important role in regulating cellular and whole-body metabolism. A-769662 only activates AMPK heterotrimers containing the B1 subunit. A-769662 activates AMPK through the beta subunit carbohydrate-binding module and the gamma subunit but not the AMP-binding sites. Solubility: Soluble in DMSO at 33mg/ml, soluble in ethanol at 5mg/ml with slight warming, very poorly soluble in water, maximum solubility in plain water is estimated to be about 50-100uM, buffers, serum, or other additives may increase or decrease the aqueous solubility. Melting Point: 277-280C Elemental Analysis: Calculated 64.71% 3.58% 7.55% 8.64% Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Produkteigenschaften

• Molekulargewicht: 360.39
• Reinheit: ~99%
• Formulierung: Supplied as an off-white powder.
• CAS Nummer: [844499-71-4]