Semi-synthetic derivative of geldanamycin, demonstrating greater stability and lower in vivo toxicity than its parent compound. 17-AAG binds specifically to heat shock protein Hsp90 in a manner similar to geldanamycin, but the binding is weaker. Solubility: Soluble in DMSO at 150mg/ml, soluble in ethanol at 5mg/ml, very poorly soluble in water, maximum solubility in plain water is estimated to be about 20-50uM, buffers, serum, or other additives may increase or decrease the aqueous solubility. Melting Point: As Reported Elemental Analysis: As Reported Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. .
Molekulargewicht:
585.69
Reinheit:
~99%
Formulierung:
Supplied as a purple powder.
CAS Nummer:
[75747-14-7]
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