AG 490 (Tyrphostin B42, N-benzyl-3,4-dihydroxy-benzylidenecyanoacetamide), CAS [[134036-52-5]]

Produktübersicht

• Artikelname: AG 490 (Tyrphostin B42, N-benzyl-3,4-dihydroxy-benzylidenecyanoacetamide), CAS [[134036-52-5]]
• Artikelnummer: USB-A0928-65
• Hersteller Artikelnummer: A0928-65
• Alternativnummer: USB-A0928-65-25
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

Specific and potent JAK2 protein tyrosine kinase inhibitor. Also, inhibits EGF receptor autophosphorylation, with IC50 of 100nM. Inhibits DNA synthesis and cell growth, induces apoptosis. Blocks growth of leukemic cells in vitro and in vivo. Synonyms: N-benzyl-3,4-dihydroxybenzylidenecyanoacetamide CAS No: 134036-52-5 Melting Point: 218-220C Solubility: Acetone, Chloroform, Ethanol, Methanol Method for Determining Identitiy: H NMR Spectroscopic Analysis TLC Conditions: SiO2, Hexane: Ethyl Acetate, 2:1, Visualized with AMCS, Single Spot, Rf=0.25. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Produkteigenschaften

• Reinheit: ~98%
• Formulierung: Supplied as a brownish yellow solid.
• CAS Nummer: [134036-52-5]