ALAS2, Recombinant, Human, His-Tag, aa136-553 (Aminolevulinate delta-Synthase 2, Delta ALA Synthetase)

Produktübersicht

• Artikelname: ALAS2, Recombinant, Human, His-Tag, aa136-553 (Aminolevulinate delta-Synthase 2, Delta ALA Synthetase)
• Artikelnummer: USB-A1210-03
• Hersteller Artikelnummer: A1210-03
• Alternativnummer: USB-A1210-03-100
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

ALAS2 specifies an erythroid-specific mitochondrially located enzyme. It catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified. Source: Recombinant protein corresponding to human ALAS, aa136-553, with N-terminal His tag, expressed in E. coli. Molecular Weight: ~46kD Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Produkteigenschaften

• Molekulargewicht: 46
• NCBI: 000032
• UniProt: P22557
• Reinheit: 90%
• Formulierung: Supplied as a liquid in 25mM Tris-HCl, pH 8.0, 100mM NaCl, 0.05% Tween 20, 3mM DTT, 20uM pyridoxal 5 phosphate monohydrate, 20% glycerol.