ANKTM1 (TRPA1, Transient Receptor Potential Cation Channel, subfamily A, Member 1, Ankyrin-like with transmembrane domains protein 1, Transformation-sensitive protein p120, Transient receptor potential cation channel subfamily A m
ANKTM1 (TRPA1, Transient Receptor Potential Cation Channel, subfamily A, Member 1, Ankyrin-like with transmembrane domains protein 1, Transformation-sensitive protein p120, Transient receptor potential cation channel subfamily A m
ANKTM1 (TRPA1, Transient Receptor Potential Cation Channel, subfamily A, Member 1, Ankyrin-like with transmembrane domains protein 1, Transformation-sensitive protein p120, Transient receptor potential cation channel subfamily A m
Artikelnummer:
USB-A2295-16A
Hersteller Artikelnummer:
A2295-16A
Alternativnummer:
USB-A2295-16A-100
Hersteller:
US Biological
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, IHC, WB
Immunogen:
Synthetic peptide corresponding to aa1-100 within the N-terminus of human ANKTM1
Transient receptor potential ion channels (TRPCs) are a superfamily of six transmembrane segment-spanning, gated cation channels. TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction. It is a transformation-associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons. Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage. It is now known that TRPA1 protein is also widely expressed outside of the CNS and is dys-regulated during oncogenic transformation. Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence/Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 2ug/ml. Detects a band at ~110kD. Immunofluorescence (IC): 1:200 Immunohistochemistry (Paraffin): 1:100-1:250 Immunohistochemistry: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
