| Antibiotic A23187 is a calcium ionophore. It causes rapid influx of calcium in various cells across biological membranes. Calcimycin was isolated from Streptomyces chartreusis in 1974. Calcimycin is a spiroketal substituted by pyrollic and benzoxazolyl groups which afford its high affinity and selectivity for calcium. Calimycin exhibits broad biological activity against bacteria, fungi and protozoa. It has found wide application as a research tool for calcium regulated cellular events. Synonyms: Calcimycin, Calcium Ionophore A23187 CAS No: 52665-69-7 Molecular Formula: C29H37N3O6 Molecular Weight: 523.6 Purity: 98% (TLC) Appearance: Crystalline solid Solubility: Soluble in DMSO, 50mg/ml with sonication. Storage and Stability: Lyophilized powder may be stored at -20C.for up to 12 months after receipt. Solutions should be stored at -20C 3 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. |
