Canertinib, Dihydrochloride (N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide Dihydrochloride, CI-1033, PD183805), CAS [[289499-45-2]]

Produktübersicht

• Artikelname: Canertinib, Dihydrochloride (N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide Dihydrochloride, CI-1033, PD183805), CAS [[289499-45-2]]
• Artikelnummer: USB-C1075-25
• Hersteller Artikelnummer: C1075-25
• Alternativnummer: USB-C1075-25-25
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

Canertinib (CI-1033, PD 183805) is a pan-erbB tyrosine kinase inhibitor. It selectively inhibits erbB1 (epidermal growth factor receptor), erbB2, erbB3, and erbB4 without blocking tyrosine kinase activity of many other receptors such as platelet-derived growth factor receptor, fibroblast growth factor receptor, and insulin receptor. Solubility: Soluble in DMSO at 100mg/ml, soluble in ethanol at 1mg/ml with warming, soluble in water at 10mg/ml with warming, buffers, serum, or other additives may increase or decrease the aqueous solubility. Compound is somewhat unstable in HPLC sample solution at room temperature. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Produkteigenschaften

• Molekulargewicht: 558.86
• Reinheit: ~99% HPLC, TLC
• Formulierung: Supplied as an off-white to pale green powder.
• CAS Nummer: [289499-45-2]