Capecitabine (5-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine, Ro-9-1978, Xeloda), CAS [[154361-50-9]]

Produktübersicht

• Artikelname: Capecitabine (5-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine, Ro-9-1978, Xeloda), CAS [[154361-50-9]]
• Artikelnummer: USB-C1077-05B
• Hersteller Artikelnummer: C1077-05B
• Alternativnummer: USB-C1077-05B-500
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

Capecitabine is a pre-prodrug of 5-fluorouracil (5-FU). After oral uptake, capecitabine is first metabolized to 5-deoxy-5-fluorocytidine (5-DFCR), which happens mainly in the liver by carboxyl-esterase. The metabolite is converted to 5-deoxy-5-fluoro-uridine (5-DFUR) by cytidine deaminase in liver and tumor tissue. Then 5-DFUR is converted to 5-FU intracellularly by thymidine phosphorylase, which is often expressed in tumor tissue. Solubility: Soluble in DMSO at 100mg/ml, soluble in ethanol at 12.5mg/ml with slight warming, soluble in water at 2mg/ml with slight warming, buffers, serum, or other additives may increase or decrease the aqueous solubility. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Produkteigenschaften

• Molekulargewicht: 359.35
• Reinheit: ~99%
• Formulierung: Supplied as a white to off-white powder.
• CAS Nummer: [154361-50-9]