CTSK (ID R222) (Cathepsin K, Cathepsin O, Cathepsin X, Cathepsin O2, CTSO2, CTSO), Rabbit
Artikelnummer:
USB-C2097-69L
Hersteller Artikelnummer:
C2097-69L
Alternativnummer:
USB-C2097-69L-200
Hersteller:
US Biological
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, FC, IHC, WB
Immunogen:
Synthetic peptide selected from the Center region of human CTSK (KLH).
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. Applications: Suitable for use in ELISA, Western Blot, Indirect Flow Cytometry, and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:50-1:100 ELISA: 1:1,000 Immunohistochemistry: 1:10-1:50 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.