CD49e (Integrin alpha-4, CD49 Antigen-like Family Member D, Integrin alpha-IV, VLA-4 Subunit alpha, ITGA4), Clone: [NKI-SAM-1], Mouse, Monoclonal

Produktübersicht

• Artikelname: CD49e (Integrin alpha-4, CD49 Antigen-like Family Member D, Integrin alpha-IV, VLA-4 Subunit alpha, ITGA4), Clone: [NKI-SAM-1], Mouse, Monoclonal
• Artikelnummer: USB-C2405-02R
• Hersteller Artikelnummer: C2405-02R
• Alternativnummer: USB-C2405-02R-100
• Hersteller: US Biological
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ELISA, FC, IHC, IP
• Immunogen: U937 cells

Produktbeschreibung

CD49e is a type I integral membrane glycoprotein, known as alpha5 integrin, VLA-5 alpha chain. It forms noncovalent heterodimer with integrin beta1 (CD29). CD49e contains two disulfide-linked subunits of 135 kD and 24 kD, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronection and neural adhesion molecule L1. It mediates monocytes migration, involves in the regulation of cells survival and apoptosis, and co-stimulates T cell activation. Applications: Suitable for use in Flow Cytometry, Immunoprecipitation, ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [NKI-SAM-1]
• Reinheit: Purified by immunoaffinity chromatography.
• Formulierung: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.