CD115 Control Peptide (c-fms, Fms, CSF-1R, M-CSFR)

Produktübersicht

• Artikelname: CD115 Control Peptide (c-fms, Fms, CSF-1R, M-CSFR)
• Artikelnummer: USB-C2447-52D1
• Hersteller Artikelnummer: C2447-52D1
• Alternativnummer: USB-C2447-52D1-1
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

Synthetic peptide coresponding to aa399-411 (Ser-Leu-Pro-Arg-Leu-Lys-Arg-Ser-Glu-Ser-Gly- Arg-Tyr) (linear) from the extracellular domain of the feline v-fms sequence. Corresponding antibody C2447-52D recognizes c-fms oncoprotein. Species crosseactivity: Human (macrophages and breast tissue) and mouse (macrophages). CD115 is also known as c-fms, marcophage colony stimulating factor receptor, or CSF-1R. It exists in immature (gp130 c-fms) and mature (gp150 c-fms) forms. CSF-1R exhibits an intrinsic tyrosine-specific protein kinase activity. It is expressed on the cells of the mononuclear phagocyte lineage. CSF-1R is an integral transmembrane glycoprotein consisting of a 512 amino acid extracellular domain that includes the CSF-1 binding site, a single 25 amino acid membrane-spanning segment, and a 435 amino acid cytoplasmic portion that includes the tyrosine kinase domain. Storage and Stability: Lyophilized powder may be stored at 4C for short-term only. Stable for 12 months at -20C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Reinheit: Highly Purified
• Formulierung: Supplied as a lyophilized powder.