C18 Ceramide (N-Stearoyl-D-sphingosine, Stearoyl Ceramide), CAS [[2304-81-6]]

Produktübersicht

• Artikelname: C18 Ceramide (N-Stearoyl-D-sphingosine, Stearoyl Ceramide), CAS [[2304-81-6]]
• Artikelnummer: USB-C2777-83
• Hersteller Artikelnummer: C2777-83
• Alternativnummer: USB-C2777-83-5,USB-C2777-83-10,USB-C2777-83-25
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

The sphingolipid ceramide is a potent inhibitor of the mitochondrial permeability transition poreand a primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1 (Lass1) in mice. Increased expression of C18 ceramide reduces cell growth in UM-SCC-22A squamous cell carcinoma cells. It is selectively downregulated in 32 human head and neck squamous cell carcinoma tumor tissues as compared to non-squamous tumor tissues. C18 Ceramide concentration is significantly higher in muscle tissue of type 2 diabetic patients compared with non-diabetic patients and is positively correlated to body mass index and inversely related to insulin sensitivity. Synonyms: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]octadecanamide, D-erythro-1,3-Dihydroxy-2-octadecanoylamido-trans-4-octadecene, N-Stearoyl- C18-sphingosine, N-Stearoyl-D-erythro-sphingosine, N-Stearoyl-D-sphingosine, N-Stearoylsphingenine, N-Stearoylsphingosine CAS No: 2304-81-6 Molecular Formula: C36H71NO3 Molecular Weight: 565.95 Purity: 95% Appearance: White solid Melting Point: 99-101.5C Solubility: Chloroform, Methanol (Sparingly), DMF Method for Determining Identity: Proton NMR and Mass Spectrometric Analysis TLC Conditions: SiO2, Dichloromethane: Methanol: 9:1, Visualized with AMCS and KMnO4, Single spot, Rf=0.60. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. Stable for 6 months after receipt.

Produkteigenschaften

• Molekulargewicht: 565.95
• Formulierung: White solid
• CAS Nummer: [2304-81-6]