2-Chloro-5-nitro-N-4-phenylbenzamide (GW9662), CAS [[22978-25-2]]
Artikelnummer:
USB-C5029-12
Hersteller Artikelnummer:
C5029-12
Alternativnummer:
USB-C5029-12-1,USB-C5029-12-5,USB-C5029-12-25
Hersteller:
US Biological
Kategorie:
Biochemikalien
A cell-permeable, selective and irreversible PPARgamma antagonist (IC50 = 3.3 nM, 32 nM, and 2 uM for PPARgamma, PPARalpha, and PPARdelta, respectively). Reported to covalently modify a cysteine residue in the binding site of PPAR. At a concentration of 10uM, also acts as an agonist of human pregnane X receptor (PXR) and farnesoid X receptor (FXR). CAS Number: 22978-25-2 Molecular Weight: 276.68 Molecular Formula: C13H9ClN2O3 Solubility: DMSO (Slightly), Methanol (Slightly) Melting Point: 157-159C Appearance: Supplied as a white to off-white solid. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
276.68
CAS Nummer:
[22978-25-2]
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