CITED 2, Recombinant, Human, aa1-270, His-Tag (Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2, MRG1, P35SRJ)

Produktübersicht

• Artikelname: CITED 2, Recombinant, Human, aa1-270, His-Tag (Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2, MRG1, P35SRJ)
• Artikelnummer: USB-C5675-06C
• Hersteller Artikelnummer: C5675-06C
• Alternativnummer: USB-C5675-06C-20, USB-C5675-06C-50, USB-C5675-06C-100, USB-C5675-06C-250
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

CITED2 is an important transcriptional cofactor involved in multiple organ development. It is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator and a proposed negative regulator for hypoxia-inducible factor (HIF)-1_ through its competitive binding with HIF-1_ to CBP/p300. CITED2 is necessary for mouse fetal liver hematopoiesis and is required for the proper formation of the hyaloid vasculature and for lens morphogenesis. Recombinant protein corresponding to aa1-270 of human CITED2, fused to His-Tag, expressed in E. coli. Swiss/Uniprot: Q99967 Molecular Weight: 29.5kD (278aa) Amino Acid Sequence: MADHMMAMNH GRFPDGTNGL HHHPAHRMGM GQFPSPHHHQ QQQPQHAFNA LMGEHIHYGA GNMNATSGIR HAMGPGTVNG GHPPSALAPA ARFNNSQFMG PPVASQGGSL PASMQLQKLN NQYFNHHPYP HNHYMPDLHP AAGHQMNGTN QHFRDCNPKH SGGSSTPGGS GGSSTPGGSG SSSGGGAGSS NSGGGSGSGN MPASVAHVPA AMLPPNVIDT DFIDEEVLMS LVIEMGLDRI KELPELWLGQ NEFDFMTDFV CKQQPSRVSC Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 29.5
• NCBI: 006070
• UniProt: Q99967
• Reinheit: 90% (SDS-PAGE). Endotoxin: 1EU/ug (LAL).
• Formulierung: Supplied as a liquid in 20mM Tris-HCl, pH8.0, 0.1M sodium chloride, 1mM DTT, 50% glycerol.