The collagen family is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral selfassociation in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function, such as bone strength and platelet activation. Applications: Suitable for use as Type IV collagen standard, Antigen for antibody production and Coating material for cell culture studies. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: For long-term storage, the purified collagen may be aliquoted and stored at -20C. Avoid repeated freezing and thawing.
Reinheit:
90% as judged by SDS-PAGE analysis and ELISA. Purified by controlled and limited pepsin digestion, followed by selective salt precipitation. Non-reduced band at 400kD.
Formulierung:
Supplied as a solution of collagen in 500mM acetic acid. The collagen may be transferred into physiological buffers by dialysis at 4C.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
