Cyclophilin B, Recombinant (PPIB, Peptidylprolyl isomerase B (Cyclophilin B), CYPB, CYP-S1, Peptidyl-prolyl cis-trans isomerase B, PPIase, Rotamase, S-cyclophilin, SCYLP)
Artikelnummer:
USB-C8855-30
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| Artikelname: | Cyclophilin B, Recombinant (PPIB, Peptidylprolyl isomerase B (Cyclophilin B), CYPB, CYP-S1, Peptidyl-prolyl cis-trans isomerase B, PPIase, Rotamase, S-cyclophilin, SCYLP) |
| Artikelnummer: | USB-C8855-30 |
| Hersteller Artikelnummer: | C8855-30 |
| Alternativnummer: | USB-C8855-30-100,USB-C8855-30-500 |
| Hersteller: | US Biological |
| Kategorie: | Molekularbiologie |
| Cyclophilin B (also known as PPIB, peptidylpropyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine Amediated immunosuppression. Recombinant human cyclophilin B was expressed in E. coli and purified by using conventional chromatography techniques Recombinant protein corresponding to aa26-216 from human cyclophilin B, expressed in E. coli. Accession: NP_000933 Molecular Weight: ~21.2kD (192aa) confirmed by MALDI-TOF Amino Acid Sequence: MLLPGPSAAD EKKKGPKVTV KVYFDLRIGD EDVGRVIFGL FGKTVPKTVD NFVALATGEK GFGYKNSKFH RVIKDFMIQG GDFTRGDGTG GKSIYGERFP DENFKLKHYG PGWVSMANAG KDTNGSQFFI TTVKTAWLDG KHVVFGKVLE GMEVVRKVES TKTDSRDKPL KDVIIADCGK IEVEKPFAIA KE Enzyme Activity: Specific activity is > 1,500 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAFP-PNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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