| Cytochalasin D is a cell permeable fungal toxin that binds to the barbed end of actin filaments inhibiting both the association and dissociation of subunits. This compound causes the disruption of actin filaments and inhibition of actin polymerization. Cytochalasin D is about 10-fold more effective than cytochalasin B and does not inhibit monosaccharide transport across cell membranes. Synonyms: Zygosporin A, (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(Acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindole-1,11(2H)-dione, (7S,13E,16S,18R,19E,21R)-[11]21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenylcytochalasa-6(12),13,19-triene-1,17-dione, (-)-Cytochalasin D, 1H-Cycloundec[d]isoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, [3S-(3R*,3aS*,4R*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*)]-, Cytochalasin D, NSC 209835 CAS No: 22144-77-0 Molecular Formula: C30H37NO6 Molecular Weight: 507.62 Purity: 98% Appearance: White lyophilized powder. Solubility: Soluble in DMSO at a concentration of 25mg/ml. Sterility: This product is not sterile. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
