The monohydrochloride salt is the form used to prepare formulations of this drug for clinical use. Note that the solubility properties of the mono- and di-HCl salts are different. Kinase inhibitor, has antivasospastic properties. Synonyms: 5-(1,4-Diazepan-1-ylsulfonyl)isoquinoline monohydrochloride, Fasudil hydrochloride, Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine monohydrochloride CAS No: 105628-07-7 Molecular Formula: C14H17N3O2SHCl Molecular Weight: 327.83 Appearance: White to off-white powder Purity (HPLC/TLC): 99% Solubility: Very soluble in water, up to about 175mg/ml , soluble in DMSO up to about 10mg/ml, not soluble in ethanol, pH of a 2% sloution is about 5.5-6, addition of an aqueous solution of this monohydrochloride salt into a buffer solution may significantly alter its solubility. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
327.83
Reinheit:
99% (HPLC/TLC)
Formulierung:
White to off-white powder
CAS Nummer:
[105628-07-7]
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