A potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis. 5-Fluoro Uracil is is an DNA/RNA synthesis inhibitor. It is used as a potent antitumor agent since it interrupts nucleotide synthetic by inhibiting thymidylate synthase. Synonyms: 5-Fluoro-2,4(1H,3H)pyrimidinedione, 2,4-Dihydroxy-5-fluoropyrimidine, 5-FU, 5-Fluoropyrimidine-2,4-diol, Adrucil, Arumel, Carac, Fluoroplex, Fluorouracil, Flurablastin, Queroplex, Ro 2-9757, Timazin, U 8953, Ulup, Flucytosine EP Impurity A, 5-FU CAS No: 51-21-8 Molecular Formula: C4H3FN2O2 Molecular Weight: 130.08 Appearance: White crystalline powder Purity: 98-102% (HPLC) Melting Point: 262-265C (dec.) (lit) Heavy Metals: 0.002% Infrared Spectrum: Conforms to reference Loss on Drying: 0.5% Residue on Ignition: 0.1% Fluorine: 13.9-15% Identity: To 5ml of solution (1:100), add 1ml of bromide water TS. The bromide color is discharged. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Warning: Highly toxic!
Molekulargewicht:
130.08
Reinheit:
98-102% (HPLC)
Formulierung:
White crystalline powder
CAS Nummer:
[51-21-8]
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