Galectin-1, Recombinant, Human (GAL1, LGALS1, GAL-1, Lectin Galactoside-binding Soluble 1, Beta-galactoside-binding Lectin L-14-I, Lactose-binding Lectin 1, S-Lac Lectin 1, Galaptin, 14kD Laminin Binding Protein, 14kD Lectin, HLBP

Produktübersicht

• Artikelname: Galectin-1, Recombinant, Human (GAL1, LGALS1, GAL-1, Lectin Galactoside-binding Soluble 1, Beta-galactoside-binding Lectin L-14-I, Lactose-binding Lectin 1, S-Lac Lectin 1, Galaptin, 14kD Laminin Binding Protein, 14kD Lectin, HLBP
• Artikelnummer: USB-G1044-47H
• Hersteller Artikelnummer: G1044-47H
• Alternativnummer: USB-G1044-47H-50,USB-G1044-47H-100
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

Lectins, of either plant or animal origin, are carbohydrate-binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T cells and T leukemia cell lines, and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5kD protein containing 134 amino acid residues. Recombinant protein corresponding to human Galectin-1, expressed in E. coli. Biological Activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5ug/ml with a peak response obtained at 250ug/ml. Amino Acid Sequence: ACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• NCBI: 005558
• UniProt: P09382
• Reinheit: 98% by SDS-PAGE gel and HPLC analyses. Endotoxin: 0.1ng/ug (1EU/ug).
• Formulierung: Supplied as a lyophilized powder from 10mM sodium phosphate, pH 7.5. Reconstitute with sterile dH2O to 0.1-1mg/ml.