| Stronger chaotropic agent than Guanidine Hydrochloride. Used in total RNA preparation as 'guanidinium solution. Guanidine Thiocyanate is used as a common protein denaturant in the purification and extraction of mRNA, nucleic acids and proteins from cellular material, acting as a strong RNase inhibitor, protecting cellular transcripts from degradation during tissue extraction. Synonyms: Guanidine isothiocyanate, Aminomethanamidine thiocyanate, Guanidinium thiocyanate CAS Number: 593-84-0 Molecular Formula: CH5N3HSCN Molecular Weight: 118.16 Purity: 99% Appearance: White, crystalline powder Solubility (6M, Water): Colorless, clear, complete Absorbance (6M): 280nm: 0.8 300nm: 0.1 410nm: 0.1 pH (1M): 4.5-7.0 Melting Point: 115-121C Heavy Metals: 0.0005% RNase: None Detected DNase: None Detected Protease: None Detected Storage: RT. Hygroscopic. Keep tightly closed and desiccated. |
